Ireland international Geordan Murphy will captain Leicester Tigers from full-back against Leinster in a pre-season friendly at Welford Road in Friday night.
Summer signings George Skivington and Thomas Waldrom will make their first appearance for the English side.
There are 10 senior internationals with Puma Marcos Ayerza and Italian Martin Castrogiovanni coming into the front row.
"We've had a pretty tough week physically, but we've not got much time left before we open the season at Northampton Saints and we need to make sure we're fit and ready," said Tigers director of rugby Richard Cockerill.
LEICESTER TIGERS (v Leinster):
15 Geordan Murphy (c)
14 Scott Hamilton
13 Matt Smith
12 Anthony Allen
11 Alesana Tuilagi
10 Toby Flood
9 Ben Youngs
1 Marcos Ayerza
2 George Chuter
3 Martin Castrogiovanni
4 Calum Green
5 George Skivington
6 Craig Newby
7 Ben Woods
8 Thomas Waldrom.
Replacements (from):
Boris Stankovich
Rob Hawkins
Dan Cole
Dave Markham
Ed Slater
Ben Pienaar
Tom Armes
James Grindal
Jeremy Staunton
Lee Robinson
Manu Tuilagi
Dan Hipkiss
Horacio Agulla
Billy Twelvetrees