The only other English side Arsenal will face last season’s beaten finalists Bayern Munich while Celtic will take on Italian champions Juventus as they look for a place in the quarter-finals.

Barcelona will take on familiar foes AC Milan with the first leg at the San Siro.

Their most recent encounter was in the quarter-finals last season, when Barca prevailed 3-1 on aggregate with Lionel Messi scoring twice in the second leg.

German champions Borussia Dortmund face a tricky clash with Shakhtar Donetsk while local rivals Schalke take on Galatasaray.

Big-spending Ligue 1 outfit Paris St Germain will fancy their chances of beating Valencia, whose form has been patchy this season, and Malaga, who are performing better in the Primera Division, meet Portuguese champions Porto.

Cristiano Ronaldo scored 118 goals in 292 appearances for United, but it was another Ronaldo - the Brazilian striker - who took the honours when the clubs last faced each other in 2003, scoring a hat-trick at Old Trafford as Real went through 6-5 on aggregate.

The clubs first met in the European Cup in April 1957, when Real triumphed 5-3 in the semi-final.

Ronaldo’s last match for United was in the Champions League final defeat by Barcelona, after which he moved to Madrid for a world record €98m transfer fee.

Celtic boss Neil Lennon called his side's draw against Juventus ``a beauty'' but very tough.

Lennon said: “Well in terms of glamour it’s a beauty. Juventus are one of the great traditional European teams. They’re current Italian champions and finished the group stage very strongly. So in terms of glamour it’s great, in terms of qualification it is going to very tough, but it could have been any of the other teams and it would have been just as tough.

“We will take it as it comes, we’re looking forward to the games now and I’m sure our supporters will be as well.

“We believe over two games anything is possible. Juventus are littered with world-class stars and have been very consistent over the last 18 months and have got a great winning mentality, but so have we.

“To come through the group as impressively as we did, you just never know where you’ll be in a month or two’s time in terms of fitness and form.”

UEFA Champions League Round of 16:

Galatasaray vs Schalke 04

Celtic vs Juventus

Arsenal vs Bayern Munich

Shakhtar Donetsk vs Borussia Dortmund

AC Milan vs Barcelona

Real Madrid vs Man Utd

Valencia vs PSG

FC Porto vs Malaga

First legs to be played February 12/13/19/20, 2013. Second legs to be played March 5/6/12/13, 2013.