The White House says the president will vote in West Palm Beach, a short drive from his Mar-a-Lago private club and, as of 2019, his official residence.
The club is located in the town of Palm Beach, which does not have any early voting locations.
Mr Trump moved his residence to Florida a year ago from New York, citing his frustration with New York’s political leadership.
He also hoped it would give him a boost in the critical battleground state.
His path to another term in the White House is virtually non-existent without a repeat victory in Florida.