Prop Pablo Federico Cardinali has been called up to Argentina’s 22-man squad for the two Test series against Ireland after Pablo Gambarini was forced to withdraw through injury.
The CASI hooker has torn a muscle in his left leg, forcing head coach Marcelo Loffreda to make further changes to his squad.
Northampton Saints hooker Matias Cortese and Hindu wing Horacio Agulla have already replaced prop Gaston De Robertis and full-back Federico Serra.
The first Test between the World Cup Group D contenders will take place at Santa Fe’s Brigadier Estanislao Lopez stadium on Saturday.
Argentina squad to face Ireland: M Avramovic (Worcester Warriors), M Ayerza (Leicester Tigers), P Bouza (Leeds), F Contepomi (Leinster), M Cortese (Northampton Saints), T De Vedia (Saracens), M Durand (Montpellier), JM Fernandez Lobbe (Sale Sharks), JC Fernandez Miranda, H Agulla (both Hindu), G Fessia (Cordoba Athletic), E Lozada, J Stuart (both CASI), S Gonzalez Bonorino (Capitolina), JM Leguizamon (London Irish), F Leonelli (Glasgow Warrios), L Lopez Fleming (Edinburgh Gunners), H Senillosa (Hindu), B Stortoni (Bristol), N Vergallo (Jockey Club Rosario), P Cardinali (CSBJ Rugby), A Vernet Basualdo (Alumni).