Ireland Under-21 Andrew Finn will start at full-back for Dolphin away to Garryowen.
The Cork club will trust the likes of Finn, Mick Manning, Donnagh Keeshan and out-half Johnny O'Mahony to deliver on the good work of a settled forward unit led by second rows James Coughlan and Dave Pomeroy.
DOLPHIN (v Garryowen): A Finn; S O'Halloran, M Manning, M Knowles, D Keeshan; J O'Mahony, K Murphy; E Knowles, D O'Farrell, J O'Sullivan, D Pomeroy, J Coughlan, G Finn, D Murphy, S Madigan.
Coach Andre Bester has gone with Johnny Lowe at full back and Ajay Derwin and Reece Spee at half-back for Belfast Harlequins' home tie with St Mary's College.
There is a familiar feel to the pack with Simon Shawe at tight-head and Darren Barbour, Paul Minnis and Chris McCarey in the back row.
BELFAST HARLEQUINS (v St Mary's College): J Lowe; W Slabbert, S Wilson, G Mitchell, C Atkinson; A Derwin, R Spee; J Carey, R Best, S Shawe, L Stevenson, L McGowan, D Barbour, P Minnis, C McCarey.
Fresh from their destruction of Cork Constitution, Buccaneers will fancy their chances of turning over Shannon in Limerick.
Tony Deignan will come in for Martin Cahill at tight-head. Chris Keane has been released by Connacht. Justin Meagher and Oisin Grennan will start on the wings.
BUCCANEERS (v Shannon): N O'Hara; J Meagher, P O’Sullivan, W Wallace, O Grennan; D Connellan C Keane; A Nash, G Halligan, T Deignan, N Smullen, C Short, G Shoeman, E Brennan, D Kelly.