Vicky Phelan will appear on Friday's Late Late Show to talk to Ryan Tubridy about the experiemental cancer treatment she is undergoing in the United States.
Vicky underwent her first week of treatment in Maryland, for what she hopes will be a process that will prolong her life and afford her more time with her family.
RTÉ's Northern Editor Tommie Gorman will be joining Tubridy to discuss Covid-19 and the border issue, and the standout moments from the four decades he has spent bringing news reports to Irish viewers and listeners.
Wellerman singer and TikTok sea shanty star Nathan Evans will speak about his meteoric rise to fame which resulted in him quitting his job and landing a record deal in the space of one week.
The Late Late Show will honour this year's Axa Community Heroes, the five finalists from across Ireland who have been doing pioneering work, going above and beyond to help others and doing it against all odds over the past year.
As a Dublin football prodigy, big things were expected of midfielder Shane Carthy when he was called up by Jim Gavin to the senior team aged just 18.
What people did not know was that since fifth year in school, Shane had been battling with his mental health and experiencing suicidal thoughts. Shane will speak to Ryan about how he got through the darkest of days.
Music on the show will be from Niamh Regan, the RTÉ Choice Music Prize nominee from Galway.
The Late Late Show airs on RTÉ One Friday, January 29th at 9.35pm.