Aer Arann has announced that it will serve Cork – Glasgow (Prestwick) from October 28.
"This is an excellent opportunity for Aer Arann to take over an existing route and develop it by offering our unique brand of quality service" said Aer Arann's commercial director Fergal Barry.
"We also very happy to ensure there is no break in service for regular customers as we introduce a second Scottish service from Cork."
Kevin Cullinane, aviation marketing manager at Cork Airport, said "This is great news for Cork Airport as we are acutely aware of the importance of ensuring that the Munster region continues to enjoy excellent connectivity to a key business and tourist destination.
"Over the past week the business community in Cork and the Greater Munster region has sought to have a new service in place from the end of October next and we are delighted that Aer Arann will provide them and their customers with an enhanced service to and from Glasgow as well as Edinburgh going forward."
Mark Rodwell, chief executive of Glasgow Prestwick Airport, said "Cork is not only an ideal city break location due to the shopping and nightlife on offer, but venture outside the city and you will find some of Ireland's best scenery."