After beating Wales in their opening Autumn Nations Cup game last weekend, Ireland will turn their sights to Twickenham tomorrow afternoon as they take on England.
Both Johnny Sexton and Robbie Henshaw will miss out through injury meaning Leinster fly half Ross Byrne will play at 10 and Chris Farrell will come in to play at outside centre.
One of the other big changes with Sexton out is who will captain the side. Earlier in the week it was confirmed that James Ryan will become the 107th player to captain Ireland this weekend.
Ryan is the fourth youngest Ireland captain of the professional era, following Peter O’Mahony, Brian O’Driscoll (both 23) and Paul O’Connell (24).
What time does the match start?
The game will kick off at 3pm on Saturday at Twickenham Stadium in London.
Where can you watch the match?
The match will be shown live on RTÉ 2, Channel 4 and on Amazon Prime in the UK.
— Irish Rugby (@IrishRugby) November 18, 2020
Speaking ahead of the game about Ross Byrne, head coach Andy Farrell said: "He deserves it, Ross deserves the chance. It’s like others. How do you find out about how they cope with the big games and the big occasions unless you give them a chance?
“We can’t just give them a chance of picking them in a squad and just training the whole time. Ross has been involved in some big games for Leinster and this is his chance to go to Twickenham and be part of a great team performance as well."
Speaking about captain James Ryan, Farrell added “I saw something nine months ago when we went into the Six Nations, the start of the Six Nations, where James Ryan started to think probably, while people are talking about me in this vein, maybe I should start doing something about it.”