“I have given this matter serious and long consideration, but ultimately have come to the conclusion that the time is right now,” said Botha, who was restricted to just two games at the recent World Cup because of injury.

“I can assure you it’s a matter I haven’t taken lightly, but sometimes your body makes up your mind for you.”

Botha has been a key figure in Ireland’s recent emergence on the world stage and took two for five in their historic victory over Pakistan at the 2007 World Cup.

In all he made 42 one-day international appearances, claiming 42 wickets at 27 while also averaging 19.58 with the bat.

“Andre has been an integral part of this Irish team’s success since his debut way back in 2001,” coach Phil Simmons said.

“He will be sorely missed, not only for his cleverly disguised slower balls or his trademark square cuts, but for his total dedication to the cause and the team.

“His courage continuing to represent Ireland with the different injuries he’s endured over the last couple of years has been incredible, and shows just what a big heart he has.”