US defence officials say the problem of unintended shipments of potentially live anthrax spores over the past decade is likely worse than first believed.
Officials now say it is possible that more than four dozen such shipments were sent to laboratories in the US and at least three to other countries. That is about twice the estimate of last week.
The Pentagon has repeatedly asserted that the mistakes posed no public health hazard.
Details on the extent of the problem are expected to be presented at a news conference by Robert Work, the deputy defence secretary.
Last Friday, Mr Work ordered a comprehensive review of laboratory procedures associated with killing, or inactivating, live anthrax for shipment.