Camelot failed in his bid to become the first Triple Crown winner since Nijinsky in 1970 as Encke claimed the Ladbrokes St Leger at Doncaster.
Camelot, trained by Aidan O’Brien and ridden by Joseph O’Brien, raced towards the rear through the early stages but made smooth progress at the half-mile pole.
All seemed to be going well as he was eased out to make his challenge two furlongs from home but Mickael Barzalona appeared to steal a slight march on Mahmood Al Zarooni’s 25-1 chance Encke, who went clear.
Camelot (2-5 favourite) gave chase but never looked like he would quite get there, finishing three-quarters of a length in arrears.