Tyrone 0-17, Derry 1-5
Tyrone hammered home the advantage at the second time of asking.
The Red hands cut loose at Casement Park to roar into the Ulster semi with a dominant display against dismal Derry.
After losing Gavin Devlin to 11th hour suspension, Stephen O'Neill to a pre-match fitness test and Cormac McAnallen with a suspected broken nose after just seven minutes, they made light of a series of setbacks to completely swamp their neighbours and fierce rivals.
It was another tense, fractious derby clash, played in front of more than 20,000, with Galway referee Michael Curley booking nine players and sending off Derry sub Padraig O'Kane in the closing stages.
For all Tyrone's dominance, it was almost an hour before they had a score from play from one of their forwards, but with man of the match Sean Cavanagh knocking them over for fun and Peter Canavan (0-8) supremely accurate from frees, they were always in control.
Cavanagh's inspirational point inside the opening 10 minutes, straight from the throw-in, was just what Tyrone needed to find an early rhythm.
Canavan just couldn't, miss from frees, converting a succession of kicks, while Paddy Bradley, a 1-6 hero less than a week earlier, missed from two relatively straightforward dead ball efforts.
The tension was everywhere, with Derry boss Mickey Moran becoming entangled with the Tyrone doctor on the sideline, and in a fractious first half, six players were booked, three from each side, with Derry's Anthony Tohill and Tyrone's Kevin Hughes fortunate not to see red.
It was 10 minutes before Derry got their opening score through centre back Kevin McCloy, and while no Tyrone forward scored from play throughout the first half, Canavan's immaculate place kicking and Cavanagh's immense presence at midfield were priceless assets.
Cavanagh's direct style saw him surge through to kick points on three occasions on that first period, Derry finishing the half with just two points on the board, the other coming from a Bradley free.
Tyrone's 0-10 to 0-2 interval lead was stretched to 11 points soon after the restart, Canavan and defender Declan McCrossan both on target.
Corner back Chris Lawn also got his name on the scoresheet as the Red Hands began to find acres of space in which to knock the ball about.
Geoffrey McGonagle came off the bench to claim 1-3, all from frees, his goal a rocked direct from a 13 metre free.
But that 34th minute effort came much too late, 14 man Derry were already a well beaten side, sub O'Kane rather harshly dismissed for a challenge on Cavanagh.