North Yorkshire Fire and Rescue officials now say 13 people have been killed in the Selby rail crash.
An estimated 60 have been injured - 30 of them seriously.
More than 100 firefighters are battling to rescue 60 people that are still trapped inside the wreckage. The scene has been described as "devastating".
All nine carriages of the morning GNER Newcastle-King's Cross intercity train - the main service from the North-East to London - derailed at Great Heck near Selby after a Land Rover and trailer skidded off a railway bridge on the M62 motorway and onto the track.
A goods train was also involved in the head-on collision, but police say they are still not certain which train was first on the scene.