Fianna Fáil leader Micheál Martin has accused the coalition of presiding over a two-tier recovery - with most people being left behind.
Addressing the Fianna Fáil Ard Fheis in Killarney tonight, Depyty Martin also vowed to oppose Government plans for Universal Health Insurance.
The FF leader told delegates that from what they've heard so far, they cannot support Government plans to introduce mandatory private health insurance.
"Society also has a duty to provide a quality and accessible health service," Deputy Martin said in his leader's address.
"We believe in a public health system and we will oppose the plan to privatise it."
Deputy Martin also accused the coalition of being unfair in how they money needed to run the country.
"At the heart of rising public anger at the raft of taxes and charges is just how unfair they are," he said.
"No matter what your income is, what pressures you are dealing with - you get the same bill."
He also said the current system of regulators setting gas and electricity prices - set up by Fianna Fáil - will have to be overhauled.
"The ESB has made €415m in profits while putting up prices by 7%," he said.
"It's time to stop this - we need a new and more accountable approach to how regulators work and how they set prices for consumers."
He also proposes a National Mental Health Authority to reduce self-harm and suicide in a similar way to how the Road Safety Authority has halved deaths on our roads.