HIQA has launched a public consultation on a draft health technology assessment (HTA) of a pre-exposure prophylaxis (PrEP) programme for people at substantial risk of HIV.
PrEP is the most recent development in the field of HIV prevention, involving the pre-emptive use of oral antiretroviral therapy in HIV negative people to prevent infection.
PrEP consists of a fixed dose combination of oral tenofovir/emtricitabine and has been licensed for use in Ireland since 2016.
A PrEP programme provides PrEP as part of a holistic service that includes frequent monitoring for adherence and side effects, testing for HIV and other STIs, and counselling and advice on safer sex practices.
HIQA’s Director of Health Technology Assessment and Deputy Chief Executive, Dr Máirín Ryan, said:
HIV infection remains a significant public health concern. There were 492 diagnoses of HIV notified in Ireland in 2017. Just over half of all notifications were in men who have sex with men.
“From reviewing the evidence, HIQA has found that PrEP is safe and highly effective at preventing HIV in people at substantial risk. Additionally, implementing a PrEP programme would be considered cost saving compared with standard care.
"The effectiveness of PrEP is strongly linked with taking the medication correctly, and PrEP must not be taken by individuals with an unrecognised HIV infection as drug resistance mutations may develop.
"This means that it is important that people taking part in a PrEP programme should receive advice on taking the medication appropriately and undergo frequent HIV testing.”
HIQA has invited members of the public to give feedback on the draft report by 28 May 2019.
The completed assessment will be submitted to the Minister for Health and the Health Service Executive as advice and published on the HIQA website.
Welcoming the publication of the draft report by HIQA, the Taoiseach said: “We want to reduce the number of new HIV diagnoses in Ireland. Increasing the availability of PrEP will help us to do so.
“This report not only confirms that PrEP can help to prevent HIV amongst those who are high risk, it also shows how a PrEP programme could save money.
The introduction of a PrEP programme, coupled with increased testing and greater awareness will help us to reduce the number of people contracting HIV.
Minister Simon Harris said: "The publication of this draft report is a significant step in the introduction of a PrEP programme in Ireland in 2019.
“Reducing the number of new HIV diagnoses in Ireland is a priority focus for me as Minister for Health. The introduction of a PrEP programme will make a significant contribution to that aim."
You can read the draft report and take part in the public consultation here.