Talks on an extension to the Croke Park agreement will resume 10.30am this morning.
It comes as the Govenment and unions begin a consultation process to try to hammer out an agreement on public service pay and conditions.
The Department of Public Expenditure is looking to cut €1bn from the pay and pensions bill through cuts to wages, overtime and premium payments and through the implementation of longer working hours.
Liam Doran from the Irish Nurses and Midwives Organisation said a stand-off is likely.
"We won't let up in this campaign," he said.
"We recognise that we have a really challenging agenda confronting the Government.
"But equally, they must recognise that we are never going to accept a situation where people on €30,000/€35,000/€40,000 - who rely on 20% of that from Sundays/night duty if providing essential services - they cannot be unfairly targeted as the outcome of these Croke Park talks."
Meanwhile frontline public servants are to hold a rally in Dublin later this evening in protest at the proposed cuts.
Members are to gather in Tallaght to register their concerns.
The rally comes as rank-and-file gardaí announce they will refuse to use their own cars, phones and laptops for official duty from next Friday.
Members of the Garda Representative Association may also picket Government-organised events.
GRA president John Parker says members are not involved in an industrial dispute as management has only proposed cuts.
However, he said the actions by GRA members could be increased in reaction to any developing situation.