With 550 people on lists for heart, lung, liver, kidney and pancreas transplants - the call is being made for a national conversation about organ donation.
This week is Organ Donor Awareness week - with the focus on families talking to each other about their willingness to donate.
Ireland's 'opt-in' system of donation is also under the spotlight.
Roscommon based journalist and advocate Gordon Ryan received a double lung transplant in Dublin's Mater Hospital five years ago.
He believes it is time for change.
He said: "At the moment there are so many people waiting on the list and I know a lot of people who died on the waiting list, who didn't get the chance.
I think if we bring in a soft opt-out system there is definitely a higher chance for people waiting for transplant.
"In that situation, it will still be vitally important for families to be consulted and they will have the final say."