As the mass exodus gets underway for the Bank Holiday weekend, motorists are being advised to watch their speed, avoid talking on phiones while driving and not to drink and drive.
Gardaí say they will be out in force over the long weekend, which is traditionally a more dangerous time. There will be checkpoints across the country.
Meanwhile, more than 250,000 passengers are expected to travel through Dublin Airport over the course of this weekend.
Almost 2,000 flights will arrive and depart between today and Monday, and passengers are being advised to check which terminal their flight is departing from before they leave home.
Garda Commissioner Martin Callinan said gardaí would be watching for speeding, drink-driving and being on the phone when behind the wheel.